Effects of Prednisone on Urinary Proteome and Disease Biomarkers in a Rat Model
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چکیده
Disease biomarkers are measurable changes associated with specific pathophysiological conditions that can be used to diagnose and monitor diseases, to predict prognoses and to reflect treatment efficiency. As a non-invasively accessible and relatively stable liquid, urine is a promising clinical sample source for biomarker discovery via proteomics approaches [1]. Recently, urinary proteomics has received increasing attention in disease biomarker research.
منابع مشابه
Title page Effects of the glucocorticoid drug prednisone on urinary proteome and candidate biomarkers
Urine is a good source of biomarkers for clinical proteomics studies. However, one challenge in the use of urine biomarkers is that outside factors can affect the urine proteome. Prednisone is a commonly prescribed glucocorticoid used to treat various diseases in the clinic. To evaluate the possible impact of glucocorticoid drugs on the urine proteome, specifically disease biomarkers, this stud...
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تاریخ انتشار 2017